This is a grindy Eldrazi mirror-ish matchup where Devourer of Destiny and Thought-Knot Seer trades matter a lot. Walking Ballista gives you a flexible threat that can ping Eldrazi Spawn tokens and, with enough counters, finish off a Basking Broodscale before it adapts. Emrakul, the Promised End is slow here, since it only gets cheap once your graveyard holds several card types, so trim it for a smoother curve. Keep Chalice of the Void, Dismember, and Kozilek's Command as your primary answers to their Eldrazi Spawn/ramp plan and Sowing Mycospawn.

Rakdos Delirium relies heavily on its graveyard for Nethergoyf sizing, Street Wraith cycling, Detective's Phoenix bestow recursion, and Stitcher's Supplier fueling delirium; Grafdigger's Cage and Tormod's Crypt directly attack that plan by stopping creatures from entering off the graveyard/library and exiling their graveyard outright. Emrakul is too slow and clunky against a deck full of cheap removal like Lightning Bolt and Flare of Malice that can also strip your hand with Thoughtseize, so it comes out, along with Glaring Fleshraker which dies too easily to their removal suite. Dismember and Kozilek's Command remain premium answers to their small creatures like Orcish Bowmasters and Moonshadow.

Esper Control leans on a small number of key cards (Solitude, Teferi, Supreme Verdict), and The Stone Brain can strip up to four copies of their most punishing card, like Solitude or Wrath of the Skies, out of hand, graveyard, and library entirely. Walking Ballista gives you a flexible threat against sweepers: if Supreme Verdict or Wrath of the Skies is coming, you can remove counters in response to ping something, and it can also chip away at Teferi and Narset loyalty or finish off a damaged or X/2 creature like Solitude. Cutting one Swamp is fine since that still leaves you on 21 lands, and your deck mostly wants colorless mana anyway. Glaring Fleshraker also comes out, because a 2/2 body is easy prey for Solitude and their sweepers and does little against a deck with so much removal and so many counterspells. Karn, the Great Creator remains strong here: its static ability shuts off Isochron Scepter, and its -2 can fetch Trinisphere from your sideboard to tax their cheap interaction like Orim's Chant and Silence.